Effects of Spiramycin on Chromosome Aberration and Micronucleus Formation in Rat Bone Marrow Cells.
نویسندگان
چکیده
منابع مشابه
Pharmaceutical effluent induced chromosome aberration in rat bone marrow cells
This paper presents the genotoxic effect of effluent from a pharmaceutical plant in Ota, Ogun state, Nigeria using the rat bone-marrow metaphase chromosome assay. The effluent was examined for some standard physical and chemical properties. Rats were intraperitoneally exposed to 1%, 5%, 10%, 25% and 50% (v/v, effluent/distilled water) concentrations of the effluent for 48 hr. Distilled water an...
متن کاملPrompt cytomolecular identification of chromosome aberration in irradiated blood cells
Background: understanding the genomic alteration induced by ionizing radiation still remains to be a methodological challenge in genetic field. The energy released from this type of radiation can potentially causes structural and numerical alterations in lymphocytes, which in turn converts them into abnormal tumor cells. Chromosomal abnormalities associated with specific type of hematological m...
متن کاملMutagenicity – in Vivo Mammalian Bone Marrow Chromosome Aberration Test
The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by the test substance to the bone marrow cells of animals, usually rodents (1)(2)(3)(4). Structural chromosome aberrations may be of two types, chromosome or chromatid. An increase in polyploidy may indicate that a chemical has the potential to induce numerical aberrations. Wi...
متن کاملRepressing of SOX6 and SOX9 in Situ Chondrogenic Differentiation of Rat Bone Marrow Stromal Cells
Introduction: SOX9 is a transcriptional activator which is necessary for chondrogenesis. SOX6 are closely related to DNA-binding proteins that critically enhance its function. Therefore, to carry out the growth plate chondrocyte differentiation program, SOX9 and SOX6 collaborate genomewide. Chondrocyte differentiation is also known to be promoted by glucocorticoids through unknown molecular mec...
متن کاملherapeutic Effect of Bone Marrow Stromal Cells & Coenzyme Q10 on Rat Models of Parkinson’S Diseas
Purpose: The assessment of the ability of combined treatment of bone marrow stromal cells graft (BMSCs) and oral administration of Coenzyme (CoQ10) in rat model of Parkinson disease as a good substitute for common current Parkinson treatments, and the comparison of this combined treatment method with alone application of these treatments. Materials and Methods: In this experimental study of mal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: CYTOLOGIA
سال: 2001
ISSN: 0011-4545,1348-7019
DOI: 10.1508/cytologia.66.395